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Table 3 Genes associated with poor prognosis in non-basal-like breast cancer

From: Analysis of high fat diet induced genes during mammary gland development: identifying role players in poor prognosis of breast cancer

Gene

Association

P-value

GPNMB

Poor prognosis

P = 0.0011

CTSL

Poor prognosis

P = 0.0022

LILRB4

Poor prognosis

P = 0.0274

DNMT3A

Poor prognosis

P = 0.0246

SLC11A1

Poor prognosis

P = 0.0461

NCF2

Poor prognosis

P = 0.0011

PTPNS1

Poor prognosis

P = 0.0008

ITGB2

Poor prognosis

P = 0.0013*

CSTB

Poor prognosis

P = 0.0332

PPGB

Poor prognosis

P = 0.0009

ADAM8

Poor prognosis

P = 0.0007

FCGR3

Poor prognosis

P = 0.0053

MMP12

-

P = 0.1092

  1. Kaplan Meier analysis was performed with all non-basal breast cancer samples (249) from the NKI dataset and the HFD genes that were found to be associated with prognosis (from Figure 1 and Additional file 1: Table S1). *5 year Kaplan Meier curve was used instead of all time points for ITGB2. Strikingly, 12 out of 13 genes were still strongly associated with poor prognosis in non-basal breast cancer samples.