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Table 1 Genotypic frequencies according to clinical parameters of the Moroccan CD patients investigated for the T300A polymorphism

From: IL23R and ATG16L1 variants in Moroccan patients with inflammatory bowel disease

   ATG16L1 T300A P value Chi-square
  N AA AG GG   Test
Age of onset 69     0.37 4.30
<17 years 10 - 8 (80.0) 2 (20.0)   
17-40 52 15 (28.8) 30 (57.7) 7 (13.5)   
>40 years 7 1 (14.3) 5 (71.4) 1 (14.3)   
Sex 69     0.57 1.14
Woman 25 4 (16.0) 17 (68.0) 4 (16.0)   
Man 44 12 (27.3) 26 (59.1) 6 (13.6)   
Type 69     0.03 13.7
Fistulizing 26 5 (19.2) 20 (76.9) 1 (3.8)   
Non fistulizing Non stenosing 24 7 (29.2) 10 (41.7) 7 (29.2)   
Stenosing 12 4 (33.3) 8 (66.7) -   
Fistulizingstenosing 7 - 5 (71.4) 2 (28.6)   
Localization 69     0.36 17.4
L1 19 1 (5.3) 13 (68.4) 5 (26.3)   
L1 + P 2 1 (50.0) 1 (50.0) -   
L2 10 4 (40.0) 4 (40.0) 2 (20.0)   
L2 + P 7 3 (42.9) 4 (57.1) -   
L3 19 6 (31.6) 11 (57.9) 2 (10.5)   
L3 + P 1 - 1 (100.0) -   
L4 2 - 1 (50.0) 1 (50.0)   
L4 + L2 4 1 (25.0) 3 (75.0) -   
P 5 - 5 (100.0) -   
SFC 69     0.09 4.8
Presence 4 - 2 (50.0) 2 (50.0)   
Absence 65 16 (24.6) 41 (63.1) 8 (12.3)   
Smoking 69     0.96 0.1
Presence 28 7 (25.0) 17 (60.7) 4 (14.3)   
Absence 41 9 (22.0) 26 (63.4) 6 (14.6)   
Appendectomy 69     0.22 3.1
Presence 9 2 (22.2) 4 (44.4) 3 (33.3)   
Absence 60 14 (23.3) 39 (65.0) 7 (11.7)   
EIM 69     0.97 0.1
Presence 39 9 (23.1) 24 (61.5) 6 (15.4)   
Absence 30 7 (23.3) 19 (63.3) 4 (13.3)   
Surgery 69     0.14 4.0
Presence 29 4 (13.8) 22 (75.9) 3 (10.3)   
Absence 40 12 (30.0) 21 (52.5) 7 (17.5)   
  1. (SFC: Similar familial cases; EIM: Extra intestinal manifestations; N: Total number; AA: wild type ATG16L1 T300A, AG: ATG16L1 T300A heterozygous variant, GG: ATG16L1 T300A homozygous variant).