Table 2 Genotypic frequencies according to clinical parameters of the Moroccan CD patients investigated for the L310P polymorphism
From: IL23R and ATG16L1 variants in Moroccan patients with inflammatory bowel disease
IL23R L310P | P value | Chi-square | ||||
|---|---|---|---|---|---|---|
N | CC | CT | TT | Test | ||
Age of onset | 69 | 0.16 | 3.7 | |||
<17 years | 10 | 6 (60.0) | 4 (40.0) | |||
17-40 | 52 | 40 (76.9) | 12 (23.1) | |||
>40 years | 7 | 7 (100.0) | ||||
Sex | 69 | 0.86 | 0.0 | |||
Woman | 25 | 19 (76.0) | 6 (24.0) | |||
Man | 44 | 34 (77.3) | 10 (22.7) | |||
Type | 69 | 0.11 | 6.1 | |||
Fistulizing | 26 | 20 (76.9) | 6 (23.1) | |||
Non fistulizing Non stenosing | 24 | 21 (87.5) | 3 (12.5) | |||
Stenosing | 12 | 9 (75.0) | 3 (25.0) | |||
Fistulizingstenosing | 7 | 3 (42.9) | 4 (57.1) | |||
Localization | 69 | 0.29 | 9.6 | |||
L1 | 19 | 16 (84.2) | 3 (15.8) | |||
L1 + P | 2 | 2 (100.0) | - | |||
L2 | 10 | 6 (60.0) | 4 (40.0) | |||
L2 + P | 7 | 7 (100.0) | - | |||
L3 | 19 | 13 (68.4) | 6 (31.6) | |||
L3 + P | 1 | - | 1 (100.0) | |||
L4 | 2 | 2 | - | |||
L4 + L2 | 4 | 3 (75.0) | 1 (25.0) | |||
P | 5 | 4 (80.0) | 1 (20.0) | |||
SFC | 69 | 0.60 | 0.3 | |||
Presence | 4 | 4 (100.0) | - | |||
Absence | 65 | 49 (75.4) | 16 (24.6) | |||
Smoking | 69 | 1.0 | 0.0 | |||
Presence | 28 | 22 (78.6) | 6 (21.4) | |||
Absence | 41 | 31 (75.6) | 10 (24.4) | |||
Appendectomy | 69 | 0.73 | 0.12 | |||
Presence | 9 | 6 (66.7) | 3 (33.3) | |||
Absence | 60 | 47 (78.3) | 13 (21.7) | |||
EIM | 69 | 0.14 | 2.14 | |||
Presence | 39 | 33 (84.6) | 6 (15.4) | |||
Absence | 30 | 20 (66.7) | 10 (33.3) | |||
Surgery | 69 | 0.30 | 1.1 | |||
Presence | 29 | 20 (69.0) | 9 (31.0) | |||
Absence | 40 | 33 (82.5) | 7 (17.5) | |||