Table 6 Genotypic frequencies according to clinical parameters of the Moroccan UC patients investigated for the L310P polymorphism
From: IL23R and ATG16L1 variants in Moroccan patients with inflammatory bowel disease
Clinical parameters | N | IL23L310P | P value | Chi-deux test | ||
|---|---|---|---|---|---|---|
CC | CT | TT | ||||
Age of onset | 30 | 0.31 | 2.34 | |||
<17 years | - | - | - | - | ||
17-40 | 21 | 16 (76.2) | 4 (19.0) | 1 (4.8) | ||
>40 years | 9 | 5 (55.6) | 4 (44.4) | - | ||
Sex | 30 | 0.30 | 2.93 | |||
Woman | 14 | 11 (78.6) | 2 (14.3) | 1 (7.1) | ||
Man | 16 | 10 (62.5) | 6 (37.5) | - | ||
Localization | 30 | 0.43 | 5.95 | |||
Leftcolitis | 11 | 6 (54.5) | 5 (45.5) | - | ||
Extensive colitis | 2 | 1 (50.0) | 1 (50.0) | - | ||
Pancolitis | 13 | 10 (76.9) | 2 (15.4) | 1 (7.7) | ||
Proctitis | 4 | 4 (100.0) | - | - | ||
SFC | 30 | 0.80 | 0.44 | |||
Presence | 1 | 1 (100.0) | - | - | ||
Absence | 29 | 20 (69.0) | 8 (27.6) | 1 (3.4) | ||
Smoking | 30 | 0.81 | 0.41 | |||
Presence | 8 | 6 (75.0) | 2 (25.0) | - | ||
Absence | 22 | 15 (68.2) | 6 (27.3) | 1 (4.5) | ||
Appendectomy | 30 | <0.0001 | 20.60 | |||
Presence | - | - | - | - | ||
Absence | 30 | 21 (70.0) | 8 (26.7) | 1 (3.3) | ||
EIM | 30 | 0.60 | 1.03 | |||
Presence | 17 | 11 (64.7) | 5 (29.4) | 1 (5.9) | ||
Absence | 13 | 10 (76.9) | 3 (23.1) | - | ||
Surgery | 30 | 0.37 | 1.98 | |||
Presence | 26 | 17 (65.4) | 8 (30.8) | 1 (3.8) | ||
Absence | 4 | 4 (100.0) | - | - | ||