Table 1 Expression of c-MET and its correlation with clinicopathological parameters in 121 cases
From: Expressions and clinical significances of c-MET, p-MET and E2f-1 in human gastric carcinoma
Parameters | Grouping | n | c-MET [case (%)] | χ2test | ||
|---|---|---|---|---|---|---|
Positive | Negative | χ2value | P value | |||
Age (year) | <60 | 40 | 28(70.0) | 12(30.0) | 0.366 | 0.562 |
≥60 | 81 | 52(64.2) | 29(35.8) | |||
Gender | Male | 77 | 52(67.5) | 25(32.5) | 1.835 | 0.168 |
Female | 44 | 28(63.6) | 16(36.4) | |||
Tumor diameter (cm) | <5 | 48 | 36(75.0) | 12(25.0) | 1.108 | 0.216 |
≥5 | 73 | 44(60.3) | 29(39.7) | |||
Location of tumor | Cardia, fundus | 20 | 17(65.0) | 3(35.0) | 11.239 | 0.003 |
Body | 37 | 30(62.2) | 7(37.8) | |||
Pylorus, antrum | 64 | 33(51.6) | 31(48.4) | |||
Lauren classification | Intestinal | 84 | 60(71.4) | 24(28.6) | 0.823 | 0.132 |
Diffuse | 37 | 20(54.1) | 17(45.9) | |||
Histological type | Grade 1 | 25 | 15(40.0) | 10(60.0) | 0.207 | 0.839 |
Grade 2 | 47 | 31(66.0) | 16(34.0) | |||
Grade 3 | 49 | 34(69.4) | 15(30.6) | |||
Invasion depth | T1 | 18 | 10(55.6) | 8(44.4) | 1.928 | 0.116 |
T2 | 32 | 20(62.5) | 12(37.5) | |||
T3 | 30 | 21(70.0) | 9(30.0) | |||
T4 | 41 | 29(70.7) | 12(29.3) | |||
Metastatic lymph node ratio | <35% | 60 | 33(55.0) | 27(45.0) | 8.237 | 0.006 |
≥35% | 61 | 47(67.0) | 14(33.0) | |||
Involving lymph node station | N0 | 43 | 22(51.2) | 21(48.8) | 9.731 | 0.021 |
N1 | 41 | 30(73.2) | 11(26.8) | |||
N2 | 26 | 18(69.2) | 8(30.8) | |||
N3 | 11 | 10(90.9) | 1(9.1) | |||
TNM stages | Ia | 16 | 9(56.2) | 7(43.8) | 10.722 | 0.015 |
Ib | 17 | 8(47.1) | 9(52.9) | |||
II | 20 | 15(75.0) | 5(25.0) | |||
IIIa | 20 | 14(70.0) | 6(30.0) | |||
IIIb | 22 | 16(72.7) | 6(26.3) | |||
IV | 26 | 18(69.2) | 8/(30.8) | |||
Survival (month) | <20 | 75 | 57(76.0) | 18(24.0) | 11.337 | 0.001 |
≥20 | 46 | 23/(50.0) | 23/(50.0) | |||