From: Expressions and clinical significances of c-MET, p-MET and E2f-1 in human gastric carcinoma
Parameters | Grouping | n | p-MET [case (%)] | χ2test | ||
---|---|---|---|---|---|---|
Positive | Negative | χ2value | P value | |||
Age (year) | <60 | 40 | 24(60.0) | 16(40.0) | 0.766 | 0.862 |
≥60 | 81 | 48(59.3) | 33(40.7) | |||
Gender | Male | 77 | 48(62.3) | 29(37.7) | 1.976 | 0.187 |
Female | 44 | 24(54.5) | 20(45.5) | |||
Tumor diameter (cm) | <5 | 48 | 33(68.8) | 15(31.3) | 1.138 | 0.236 |
≥5 | 73 | 39(53.4) | 34(46.6) | |||
Location of tumor | Cardia, fundus | 20 | 15(75.0) | 5(25.0) | 10.252 | 0.009 |
Body | 37 | 27(73.0) | 10(27.0) | |||
Pylorus, antrum | 64 | 30(46.9) | 34(53.1) | |||
Lauren classification | Intestinal | 84 | 55(65.5) | 29(34.5) | 0.924 | 0.186 |
Diffuse | 37 | 17(45.9) | 20(54.1) | |||
Histological type | Grade 1 | 25 | 13(52.0) | 12(48.0) | 0.192 | 0.741 |
Grade 2 | 47 | 28(59.6) | 19(40.4) | |||
Grade 3 | 49 | 31(63.3) | 18(36.7) | |||
Invasion depth | T1 | 18 | 9(50.0) | 9(50.0) | 1.996 | 0.156 |
T2 | 32 | 18(56.3) | 14(43.8) | |||
T3 | 30 | 19(63.3) | 11(36.7) | |||
T4 | 41 | 26(63.4) | 15(36.6) | |||
Metastatic lymph node ratio | <35% | 60 | 30(50.0) | 30(50.0) | 8.556 | 0.007 |
≥35% | 61 | 42(68.9) | 19(31.1) | |||
Involving lymph node station | N0 | 43 | 20(46.5) | 23(53.5) | 9.651 | 0.042 |
N1 | 41 | 27(65.9) | 14(34.1) | |||
N2 | 26 | 16(61.5) | 10(38.5) | |||
N3 | 11 | 9(81.8) | 2(18.2) | |||
TNM stages | Ia | 16 | 8(50.0) | 8(50.0) | 10.887 | 0.016 |
Ib | 17 | 8(47.1) | 9(52.9) | |||
II | 20 | 13(65.0) | 7(35.0) | |||
IIIa | 20 | 13(65.0) | 7(35.0) | |||
IIIb | 22 | 14(63.6) | 8(36.4) | |||
IV | 26 | 16(61.5) | 10/38.5) | |||
Survival (month) | <20 | 75 | 52(69.3) | 23(30.7) | 10.006 | 0.004 |
≥20 | 46 | 20/(43.5) | 26/(56.5) |