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Table 2 Species drug combinations with changes ≥ 10% in the category susceptible in cumulative AST data prepared form representative strain collections

From: Impact of minimal inhibitory concentration breakpoints on local cumulative bacterial susceptibility data and antibiotic consumption

 

Assignment of strain collections to AST categories (%)

 

DIN

EUCAST*

Species#/drug

S

I

R

S

I

R

K. pneumoniae (n = 100)

      

pip./taz.

72

24

4

84*

9

7

P. mirabilis (n = 100)

      

ciprofloxacin

78

15

7

68

10

22

M. morganii (n = 30)

      

cefotaxime

83

13

3

73

10

17

ciprofloxacin

100

0

0

87*

13

0

P. aeruginosa (n = 100)

      

piperacillin

40

56

4

91*

0

9

ciprofloxacin

88

5

7

76*

12

12

gentamicin

73

22

5

95*

0

5

  1. *Asterisks indicate a significant (p < 0.05) difference of the number of susceptible isolates according to EUCAST MIC breakpoints compared to DIN.
  2. #No variation ≥ 10% in the category susceptible was found for E. coli (n = 100), E. cloacae (n = 100), S. marcescens (n = 37), C. freundii (n = 20), S. maltophilia (n = 47), S. aureus (n = 100), coagulase negative staphylococci (n = 100), E. feacalis (n = 100), and E. faecium (n = 100).