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Table 3 Effect of AST breakpoint on cumulative AST data prepared form representative strain collections of ESBL-expressing E. coli , MDR P. aeruginosa , and MRSA isolates

From: Impact of minimal inhibitory concentration breakpoints on local cumulative bacterial susceptibility data and antibiotic consumption

  Assignment of strain collections to AST categories (%)
  DIN  
Species/drug S I R S I R
E. coli ESBL (n = 35)       
pip./taz. 51 31 17 80* 6 14
MDR P. aeruginosa (n = 26)       
piperacillin 0 42 58 15* 0 85
ceftazidime 38 31 31 50 0 50
ciprofloxacin 27 15 58 8 19 73
gentamicin 42 19 38 62 0 38
  1. MRSA (n = 19) - no variation ≥ 10% in the category susceptible.
  2. *Asterisks indicate a significant (p < 0.05) difference of the number of susceptible isolates according to EUCAST MIC breakpoints compared to DIN.