Impact of minimal inhibitory concentration breakpoints on local cumulative bacterial susceptibility data and antibiotic consumption

Table 3 Effect of AST breakpoint on cumulative AST data prepared form representative strain collections of ESBL-expressing E. coli , MDR P. aeruginosa , and MRSA isolates

	Assignment of strain collections to AST categories (%)
	DIN
*Species*/drug	S	I	R	S	I	R
E. coli ESBL (n = 35)
pip./taz.	51	31	17	80^*	6	14
MDR P. aeruginosa (n = 26)
piperacillin	0	42	58	15^*	0	85
ceftazidime	38	31	31	50	0	50
ciprofloxacin	27	15	58	8	19	73
gentamicin	42	19	38	62	0	38

MRSA (n = 19) - no variation ≥ 10% in the category susceptible.
^*Asterisks indicate a significant (p < 0.05) difference of the number of susceptible isolates according to EUCAST MIC breakpoints compared to DIN.

ISSN: 1756-0500