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Table 1 IC 50 values and selectivity indices (SI) of O. syriacum and T. vulgaris extracts

From: In vitro inhibition of human leukemia THP-1 cells by Origanum syriacum L. and Thymus vulgaris L. extracts

Plant extract

IC50(95% Confidence interval) in mg/mL

P-value

SI

THP-1 Cells

PBMCs

O. syriacum

2.126 (1.934 - 2.339)

0.425 (0.339 - 0.533)

< 0.0001

0.2

T. vulgaris

0.157 (0.133 - 0.186)

0.334 (0.311 - 0.359)

< 0.0001

2.1

  1. All values were determined by GraphPad Prism nonlinear regression analysis. The Log (inhibitor) vs. response - Variable slope (four parameters) equation was used for best fit of all extracts curves. In all of these curves, the bottom was constrained to zero value. SI = IC50 of extract in the normal cell line/IC50 of the same extract in cancer cell line.
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BMC Research Notes

ISSN: 1756-0500

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