Table 2 Fold change of gene expression in retinal pigment epithelial cells exposed to bevacizumab compared to human vascular endothelial growth factor-treatedcontrol
Gene symbol | Gene name | Bevacizumab/control | Grade |
|---|---|---|---|
MAPK3 | Mitogen-activated protein kinase 3 | 19.7066 | A |
NFATC2 | nuclear factor of activated T-cells | 5.2333 | A |
NRP1 | Neuropilin 1 | 7.0536 | A |
SPHK1 | Sphingosine kinase 1 | 22.0982 | A |
VEGFA | Vascular endothelial growth factor A | 61.0411 | A |
NOS3 | Nitric oxide synthase | -170.2534 | A |
NRP2 | Neuropilin 2 | -6.2684 | A |
PIK3R3 | Phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -4.0044 | A |
PIK3R5 | Phosphoinositide-3-kinase, regulatory subunit 5 | -14.6532 | B |
PLA2G2A | Phospholipase A2, group IIA | -21.5369 | B |
PLA2G2D | Phospholipase A2, group IID | -40.967 | B |
PLA2G2E | Phospholipase A2, group IIE | -31.6041 | B |
PLA2G2F | Phospholipase A2, group IIF | -212.0617 | B |