Figure 2

Partial sequencing chromatograms of the VHL gene containing rs1642742 in reverse direction. The rs1642742 is represented by a rectangular frame. Normal tissue (A) and tumor tissue (B) from heterozygous individual #1 in Table 1 show LOH. (B) and (D) represent examples of LOH of the A allele at rs1642742 of VHL gene in the tumor tissues from RCC patients (#1 and #7). (C) represents loss of the G allele (#2).