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Table 2 Comparison of the frequency distributions of rs779805 and rs1642742 of VHL gene in the germline DNA of RCC patients with normal controls

From: Two single nucleotide polymorphisms in the von Hippel-Lindau tumor suppressor gene in Taiwanese with renal cell carcinoma

  rs779805 rs1642742  
  19 RCCs# 616 controls# 19 RCCs# 616 controls#
Genotype distribution     
 AA 12 (63.16%) 470 (76.30%) 11 (57.89%) 467 (75.81%)
 AG 7 (36.84%) 132 (21.43%) 8 (42.10%) 134 (21.75%)
 GG 0 14 (2.27%) 0 15 (2.44%)
Allele frequency     
 A allele 31 (81.58%) 1072 (87.01%) 30 (78.95%) 1068 (86.69%)
 G allele 7 (18.42%) 160 (12.99%) 8 (21.05%) 164 (13.31%)
Homozygous genotype     
 (AA or GG genotype) 12 (63.16%) 484 (78.57%) 11 (57.89%) 482 (78.25%)
Heterozygous genotype     
 (AG genotype) 7 (36.84%) 132 (21.43%) 8 (42.01%) 134 (21.75%)
Allele carriage frequency     
 A allele (AA+AG) 19 (100%) 602 (97.73%) 19 (100%) 601 (97.56%)
 G allele (AG+GG) 7 (36.84%) 146 (23.70%) 8 (42.10%) 149 (24.19%)
  1. #Data presented as number of cases and percentage; bold text means statistical significance was reached, p < 0.05, in the comparison of germline DNA between RCC patients and controls.