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Table 1 Patient characteristics (N = 90)

From: Leptomeningeal involvement in B-cell chronic lymphocytic leukemia: a case report and review of the literature

Data   
Age, median (range) 65 (33–89)
Missing data 4  
Gender, N (%)
Male 55 (61)
Female 31 (35)
Missing data 4 (4)
Stage, N (%)
Rai 0,1 and Binet A 34 (38)
Rai 2 and Binet B 16 (18)
Rai 3,4 27 (30)
Missing data 13 (14)
Time to CNS disease, N (%)
Until 1 year 35 (39)
>1 ≤ 5 year 29 (33)
> 5 year 13 (14)
Missing data 13 (14)
CNS site of involvement, N (%)
Leptomeningeal 53 (59)
Leptomeningeal and brain parenchima 4 (5)
Brain parenchima 12 (13)
Othersa 21 (23)
Neuroimaging, N (%)
Positive 23 (26)
Negative 23 (26)
Missing data 44 (48)
Cerebrospinal fluid, N (%)
Positive 57 (63)
Negative 7 (8)
Missing data 26 (29)
Histology, N (%)
Yes (positive) 15 (17)
No 75 (83)
Treatment
IT + systemic chemotherapy 17 (19)
IT + radiation therapy 13 (14)
IT chemotherapy 13 (14)
IT + systemic + radiation therapy 8 (9)
Systemic chemotherapy 8 (9)
Systemic + radiation therapy 6 (7)
Radiation therapy 5 (6)
None 9 (10)
Not available 11 (12)
Survival status, N (%)
Alive 38 (42)
Dead 38 (42)
Missing data 14 (16)
  1. IT = intrathecal treatment.
  2. ahypothalamus, optic nerve, pituitary, skull base thickening, spinal cord, dura mater, epidural.