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Table 1 Patient characteristics (N = 90)

From: Leptomeningeal involvement in B-cell chronic lymphocytic leukemia: a case report and review of the literature

Data

  

Age, median (range)

65

(33–89)

Missing data

4

 

Gender, N (%)

Male

55

(61)

Female

31

(35)

Missing data

4

(4)

Stage, N (%)

Rai 0,1 and Binet A

34

(38)

Rai 2 and Binet B

16

(18)

Rai 3,4

27

(30)

Missing data

13

(14)

Time to CNS disease, N (%)

Until 1 year

35

(39)

>1 ≤ 5 year

29

(33)

> 5 year

13

(14)

Missing data

13

(14)

CNS site of involvement, N (%)

Leptomeningeal

53

(59)

Leptomeningeal and brain parenchima

4

(5)

Brain parenchima

12

(13)

Othersa

21

(23)

Neuroimaging, N (%)

Positive

23

(26)

Negative

23

(26)

Missing data

44

(48)

Cerebrospinal fluid, N (%)

Positive

57

(63)

Negative

7

(8)

Missing data

26

(29)

Histology, N (%)

Yes (positive)

15

(17)

No

75

(83)

Treatment

IT + systemic chemotherapy

17

(19)

IT + radiation therapy

13

(14)

IT chemotherapy

13

(14)

IT + systemic + radiation therapy

8

(9)

Systemic chemotherapy

8

(9)

Systemic + radiation therapy

6

(7)

Radiation therapy

5

(6)

None

9

(10)

Not available

11

(12)

Survival status, N (%)

Alive

38

(42)

Dead

38

(42)

Missing data

14

(16)

  1. IT = intrathecal treatment.
  2. ahypothalamus, optic nerve, pituitary, skull base thickening, spinal cord, dura mater, epidural.