Table 1 Demographic and clinical characteristics of 901 PD patients
Characteristics | Total (n = 901) | Gulf of Bohai (n = 283) | Changjian Delta (n = 275) | Pearl-River Delta (n = 110) | Mid-west Area (n = 233) | P Value | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Men, n (%) | 562 | (62.4) | 180 | (63.6) | 174 | (63.3) | 67 | (60.9) | 141 | (60.5) | 0.87 |
Age at survey (yr) | 67.0 | (15.0) | 68.0 | (15.0) | 66.0 | (15.0) | 67.5 | (13.0) | 67.0 | (15.0) | 0.43 |
<60, n (%) | 254 | (28.2) | 76 | (26.9) | 87 | (31.6) | 27 | (24.5) | 97 | (41.6) | |
60-69, n (%) | 266 | (29.5) | 81 | (28.6) | 111 | (40.4) | 36 | (32.7) | 72 | (30.9) | |
≥70, n (%) | 381 | (42.3) | 126 | (44.5) | 77 | (28.0) | 47 | (42.7) | 64 | (27.5) | |
Education (yr) | 10.7 | (4.6) | 12.2 | (4.2) | 10.3 | (4.5) | 9.4 | (5.1) | 10.0 | (4.3) | <0.001 |
Occupation, n (%) | <0.001 | ||||||||||
Labor/ Service, n (%) | 392 | (43.5) | 89 | (31.5) | 146 | (53.1) | 58 | (52.7) | 99 | (42.5) | |
Administrative, n (%) | 253 | (28.1) | 107 | (37.8) | 51 | (18.5) | 24 | (21.8) | 71 | (30.5) | |
Professional, n (%) | 256 | (28.4) | 87 | (30.7) | 78 | (28.4) | 28 | (25.5) | 63 | (27.0) | |
Living on personal income, n (%) | 722 | (80.1) | 261 | (92.2) | 212 | (77.1) | 69 | (62.7) | 180 | (77.3) | <0.001 |
Age of 1st symptom onset (yr) | 61.0 | (15.0) | 60.0 | (15.0) | 60.0 | (16.0) | 61.5 | (18.0) | 63 · 0 | (14.0) | 0.35 |
Age at diagnosis (yr) | 62.8 | (15.6) | 61.9 | (16.0) | 61.7 | (15.6) | 63.1 | (17.8) | 63.8 | (13.5) | 0.29 |
Months from onset to 1st visit | 3.0 | (12.0) | 4.0 | (12.0) | 3.0 | (9.0) | 3.0 | (12.0) | 3.0 | (12.0) | 0.11 |
Tremor as 1st symptom, n (%) | 586 | (65.4) | 185 | (65.4) | 170 | (61.8) | 75 | (68.2) | 156 | (67.0) | 0.55 |
Resting tremor, n (%) | 758 | (84.1) | 241 | (85.2) | 233 | (84.7) | 88 | (80.0) | 143 | (84.1) | 0.64 |
Rigidity, n (%) | 832 | (92.3) | 270 | (95.4) | 253 | (92.0) | 102 | (92.7) | 207 | (88.8) | 0.05 |
Bradykinesia, n (%) | 881 | (97.8) | 281 | (99.3) | 269 | (97.8) | 108 | (98.2) | 223 | (95.7) | 0.05 |
Hoehn-Yahr stage, n (%) | <0.001 | ||||||||||
1.0-1.5 | 173 | (19.2) | 44 | (15.6) | 71 | (18.9) | 14 | (12.7) | 44 | (18.9) | |
2.0-2.5 | 560 | (62.2) | 189 | (66.8) | 151 | (58.4) | 84 | (76.4) | 136 | (58.4) | |
3.0 | 114 | (12.6) | 34 | (12.0) | 45 | (12.9) | 5 | (4.6) | 30 | (12.9) | |
4.0-5.0 | 54 | (6.0) | 16 | (5.7) | 8 | (9.9) | 7 | (6.4) | 23 | (9.9) | |
UPDRS-II, scores | 11.0 | (8.0) | 10.0 | (8.0) | 10.0 | (11.0) | 11.0 | (7.0) | 12.0 | (11.0) | <0.001 |
UPDRS-III, scores | 25.0 | (20.0) | 27.0 | (20.0) | 23.0 | (18.0) | 24.0 | (19.0) | 26.0 | (23.0) | 0.02 |
PD duration, months | 50.0 | (58.0) | 56.0 | (61.0) | 50.0 | (56.0) | 49.0 | (56.0) | 44.0 | (53.0) | <0.001 |
Hoehn-Yahr stage 1.0-2.0 | 37.0 | (43.0) | 41.0 | (48.0) | 40.0 | (38.0) | 37.0 | (48.0) | 27.0 | (45.0) | |
Hoehn-Yahr stage 2.5-5 | 70.0 | (70.0) | 82.0 | (78.5) | 72.0 | (69.0) | 76.0 | (75.5) | 56.0 | (53.5) | |
MMSE score < cutoff, n (%) | 225 | (25.0) | 55 | (19.4) | 61 | (22.2) | 30 | (27.3) | 79 | (33.9) | 0.005 |
Depressive symptom, n (%) | 406 | (45.1) | 100 | (35.3) | 113 | (41.1) | 60 | (54.5) | 133 | (57.1) | 0.004 |