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Table 2 Immunohistochemical staining results of Leydig cell tumors

From: Leydig cell tumors of the testis: a case report

  Marker Immunoreactivity
Benign Leydig cell tumors Inhibin A +
Calretinin* +
Melan A (Mart-1) +
Vimentin* +
S-100 +
Synaptophysin* +/−
Chromogranin +
CD99* +
P- /N-Cadherin +
RLF/INSL3 +
StAR protein +
SF-1 +
Cytokeratin* -
PLAP -
CD-30 -
Oct3/4 -
Malignant Leydig cell tumors Ki67 +
  p53 +
  Bcl2 +
  1. Abbreviations: RLF/INSL3 Relaxin-like factor/Insulin-like 3, StAR-protein Steroidogenic Acute Regulatory protein, SF-1 Steroidogenic factor 1, PLAP Placental Alkaline Phosphatase. *Immunohistochemical tests performed in our case.