Leydig cell tumors of the testis: a case report

BMC Research Notes

Table 2 Immunohistochemical staining results of Leydig cell tumors

	Marker	Immunoreactivity
Benign Leydig cell tumors	Inhibin A	+
	Calretinin*	+
	Melan A (Mart-1)	+
	Vimentin*	+
	S-100	+
	Synaptophysin*	+/−
	Chromogranin	+
	CD99*	+
	P- /N-Cadherin	+
	RLF/INSL3	+
	StAR protein	+
	SF-1	+
	Cytokeratin*	-
	PLAP	-
	CD-30	-
	Oct3/4	-
Malignant Leydig cell tumors	Ki67	+
	p53	+
	Bcl2	+

Abbreviations: RLF/INSL3 Relaxin-like factor/Insulin-like 3, StAR-protein Steroidogenic Acute Regulatory protein, SF-1 Steroidogenic factor 1, PLAP Placental Alkaline Phosphatase. *Immunohistochemical tests performed in our case.

ISSN: 1756-0500