Table 1 Baseline characteristics of patients enrolled in NLT group compared to UC group
Patient characteristic | Nurse-led titration group (NLT) | Usual care group (UC) | P value |
|---|---|---|---|
Number of patients | Number of patients | ||
(n = 12) | (n = 13) | ||
Demographic characteristics | |||
Age | 65 ± 14.2 | 68 ± 18.7 | 0.7 |
Male | 9 | 9 | 0.6 |
Living alone | 4 | 4 | 0.6 |
Caucasian | 7 | 10 | 0.5 |
Co-morbidities | |||
Mean Charlson Co-morbidity Index score (±SD) | 2.7 ± 2 | 2.4 ± 1.3 | 0.7 |
Chronic obstructive pulmonary disease | 5 | 2 | 0.2 |
Diabetes mellitus | 3 | 4 | 0.5 |
Chronic renal impairment | 2 | 3 | 1.0 |
Hypertension | 3 | 8 | 0.07 |
Dyslipidaemia | 3 | 5 | 0.4 |
Atrial fibrillation | 1 | 5 | 0.2 |
Ischaemic heart disease | 4 | 3 | 0.5 |
Heart failure profile | |||
NYHA class I/II/III/IV | 17/3/1 | 7/4/2/0 | 0.02 |
LVEF( ±SD) | 34% ± 9% | 31% ± 11% | 0.5 |
Pharmacotherapy at baseline | |||
Beta-blocking agents | |||
ACEIs | 11 | 10 | 0.6 |
ARBs | 0 | 4 | 0.09 |
Spironolactone | 6 | 4 | 0.3 |
Loop diuretic | 7 | 4 | 0.2 |
Digoxin | 1 | 1 | 0.9 |
Nitrates | 3 | 2 | 0.9 |
Aspirin | 4 | 8 | 0.2 |
Warfarin | 2 | 1 | 0.5 |
Amiodarone | 1 | 2 | 0.6 |
Statin | 3 | 4 | 0.5 |
Quality of life | |||
MLWHF (±SD) | 33 ± 20 | 37.6 ± 28 | 0.7 |
CDS (±SD) | 90 ± 27 | 77 ± 27 | 0.3 |