Changes of serum Trx1, CEA, and CA15-3 levels in patients breast cancer as a function of the progress of the cancer. The individual mean value (n = 3) was depicted as a scatter dot plot. The mean value of each group is shown by horizontal lines, and the 95% of confidence interval (CI) is displayed by vertical lines. Abbreviations: BCL, lobular carcinoma of breast; BCD; ductal carcinoma of breast; NF, normal female; I, II, III; grade 1, II, III of breast cancer, corresponding cancer grades, respectively. The average data of Trx1, CEA, and CA15-3 levels in sera were displayed in panels A, B, and C, respectively.