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Table 3 Parameters from ROC analysis on serum Trx1 levels in patients with various cancers

From: Thioredoxin 1 as a serum marker for breast cancer and its use in combination with CEA or CA15-3 for improving the sensitivity of breast cancer diagnoses

Type of cancer AUC* (±SEM) Sensitivity (%) Specificity (%) Criterion (ng/ml) # of serum (Grade)
Breast/NFM 0.911 ± 0.179 89.3 78.0 >32.3390 197 (I/II/III)
Colorectal/NFM 0.687 ± 0.0425 68.3 61.0 >29.0533 64 (I/II/III)
Kidney/NFM 0.633 ± 0.0617 46.7 81.0 >32.9986 30 (I/II)
Lung/NFM 0.643 ± 0.0381 54.1 73.0 >31.1820 108 (I/II/III/IV)
Normal Control - - - - 100 F/M: 50 F / 50 M
  1. *P < 0.0001.