|
Parameter
|
Group
|
Baseline
|
60 min
|
120 min
|
180 min
|
240 min
|
|---|
|
CO
|
C-group
|
5.1 (0.6)
|
5.3 (0.9)
|
5.2 (1.1)
|
5.1 (0.8)#
|
4.8 (0.9)
|
|
(l/min)
|
P-group
|
5.4 (0.6)
|
5.2 (0.8)
|
5.1 (0.8)
|
3.8 (0.9)*
|
4.3 (0.6)*
|
|
SVR
|
C-group
|
905.9 (155)
|
876.8 (145,2)
|
896.4 (250,8)
|
835.2 (153.9)#
|
871.7 (134.4)
|
|
(dynes/sec/cm-5)
|
P-group
|
960.7 (131)
|
970.7 (180,5)
|
946.9 (120,4)
|
1299.2 (201.3)***
|
1128.8 (183.3)
|
|
PVR
|
C-group
|
128.6 (41.6)
|
123.9 (21.8)
|
137.8 (25.1)
|
144.5 (28.3)
|
211.9 (100.1)
|
|
(dynes/sec/cm-5)
|
P-group
|
134.7 (23)
|
138.2 (18)
|
151.6 (27.1)
|
249.4 (112.9)
|
250.6 (82)*
|
|
ICP
|
C-group
|
16.3 (2.9)
|
17.3 (3.1)
|
19.9 (4.9)
|
20.8 (6.0)
|
20.6 (5.8)
|
|
(mmHg)
|
P-group
|
16.9 (5.9)
|
21.6 (4.9)
|
24.0 (7.3)***
|
26.7 (4.0)***
|
26.9 (5.9)***
|
|
CPP
|
C-group
|
54.0 (11.0)
|
52.8 (11.7)
|
40.1 (20.2)
|
45.1 (15.2)
|
44.4 (13.7)
|
|
(mmHg)
|
P-group
|
52.7 (5.0)
|
50.9 (5.0)
|
48.4 (6.8)
|
50.6 (7.6)
|
47.0 (7.4)
|
-
Values are presented as mean with SD in parentheses. Control group: C-group; Intervention group: P-group; CO: cardiac output; SVR: systemic vascular resistance; PVR: pulmonary vascular resistance; ICP: intracranial pressure; CPP: cerebral perfusion pressure.
-
*: P < 0.05 ***: P < 0.001; within group difference compared with baseline values;
-
#: P < 0.05; between group differences, same time.
