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Figure 1 | BMC Research Notes

Figure 1

From: Growth differentiation Factor 11 is an encephalic regionalizing factor in neural differentiated mouse embryonic stem cells

Figure 1

Effect of SB431542 (SB), and GDF11 on neural patterning. The effect of different concentrations of SB, and GDF11 on the expression level of different regional markers was assessed by qRT-PCR. The markers used were Bf1 (telencephalon) (A), Pax6 (diencephalon) (B), Otx1 (prosencephalon and mesencephalon) (C), En1 (mesen- and metencephalon) (D), Gbx2 (metencephalon) (E), Krox20 (myelencephalon) (F) and Hoxc9 (spinal cord) (G). The results presented here are the means of three independent experiments with the standard error of the mean. Statistically significant changes in expression level (p < 0.05) are marked with an asterisk in the graphs, as compared to “control” (sample 6).

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