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Table 2 Patients characteristics in individual groups

From: Association between single-nucleotide polymorphisms and early spontaneous hepatitis B virus e antigen seroconversion in children

  

G1: Early (N = 52)

G2: Late or no seroconversion (N = 57)

Univariate

Multivariate

    

P value

P value

Age at initial visit (year)

 

0-10 (Median 2.8)

0-44 (Median 28)

< 0.00005

****

Gender (Male/Female)

 

28/24

5/52

< 0.00005

0.001

ALT level (IU/L) at initial visit

 

10-725 (Median 80.5)

7-767 (Median 23)

< 0.00005

0.489

Duration of follow-up period (year)

 

1-21 (Median 10.0)*

1-25 (Median, 6.0)

0.6218

0.013

Age at HBe seroconversion

 

1-10 (Median 6.5)

21-34 (Median 25)**

Not done

Not done

Serum HBV DNA level at last visit (log copies/mL)

 

2.5-8.7 (Median 4.8)***

3.0-9.0 (Median 8.5)

< 0.00005

0.003

Transmission route

Mother-to-child

43

37

Mother-to-child

 
 

Household contacts

5

4

v.s. Non Mother-to-child

 
 

Blood transfusion

1

0

0.036

0.016

 

Unknown

3

16

  

HBV Genotype

A

0

1

Genotype C

 
 

B

7

10

v.s. Non genotype C

 
 

C

44

45

0.445

0.221

 

D

1

1

  
  1. *Data of 51 patients were available.
  2. **Of the 57 patients, 17 patients archived seroconversion.
  3. *** Of the 57 patients, 23 patients were positive for serum HBV DNA and the remaining 28 patients were negative for HBV DNA.
  4. ****Omitted from model in order to permit convergence to finite maximim likelihood estimates.