Skip to main content

Advertisement

Table 2 Variant frequency in high grade serous ovarian carcinoma versus normal ovary

From: Molecular characterization of serous ovarian carcinoma using a multigene next generation sequencing cancer panel approach

Gene/Variant frequency APC EGFR FGFR3 KDR KIT MET PDGFRA PIK3CA RET SMO STK11 TP53
Tumour 89% 67% 100% 89% 22% 11% 100% 11% 67% 22% 22% 100%
Normal 100% 30% 100% 70% 0% 10% 100% 0% 60% 10% 0% 0%
p value 0.4737 0.1789 1 0.5820 0.2105 1 1 0.4737 1 0.5820 0.2105 0.0001***
  1. ***Statistically significant value.
  2. TP53 alterations are statistically significantly more frequent in serous ovarian carcinoma.