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Table 2 Means (SD) for hypertension, coronary artery disease, blood pressure and body mass index according to syndecan-4 polymorphisms

From: Contribution of syndecan-4 genetic variants to hypertension, the TAMRISK study

    

P*

  

rs4599

C/C

T/C

T/T

Additive

Dominant (TT)

Recessive (CC)

n

32

287

448

   

Hypertension %

39

31

35

0.496

0.225

0.334

Coronary artery disease % (n=31)

10

5

3

0.057

0.061

0.108

Systolic blood pressure (mm Hg) at 45

133.6 (15.3)

132.2 (13.5)

133.0 (14.3)

0.735

0.542

0.750

Systolic blood pressure (mm Hg) at 50

136.8 (12.7)

134.7 (16.7)

135.3 (17.1)

0.771

0.738

0.485

Diastolic blood pressure (mm Hg) at 45

83.6 (7.5)

85.1 (9.0)

85.6 (9.5)

0.471

0.329

0.330

Diastolic blood pressure (mm Hg) at 50

87.3 (8.4)

88.0 (10.1)

88.1 (9.7)

0.904

0.780

0.640

Body mass index (kg/m 2 ) at 45

27.4 (4.5)

26.5 (4.3)

26.3 (4.2)

0.368

0.368

0.215

Body mass index (kg/m 2 ) at 50

27.6 (4.5)

26.9 (4.7)

26.9 (4.7)

0.776

0.776

0.438

rs1981429

G/G

T/G

T/T

Additive

Dominant (TT)

Recessive (GG)

n

185

396

186

   

Hypertension %

32

32

41

0.074

0.015

0.283

Coronary artery disease % (n=31)

2

3

7

0.013

0.010

0.056

Systolic blood pressure (mm Hg) at 45

133.6 (15.7)

131.5 (13.7)

134.2 (14.2)

0.086

0.108

0.379

Systolic blood pressure (mm Hg) at 50

133.1 (16.7)

135.4 (17.3)

136.2 (15.9)

0.157

0.252

0.064

Diastolic blood pressure (mm Hg) at 45

85.9 (10.0)

84.4 (8.8)

86.7 (9.4)

0.018

0.025

0.408

Diastolic blood pressure (mm Hg) at 50

87.1 (9.6)

88.4 (10.1)

87.9 (9.2)

0.330

0.928

0.161

Body mass index (kg/m 2 ) at 45

26.4 (4.0)

26.1 (4.0)

27.2 (4.7)

0.024

0.008

0.832

Body mass index (kg/m 2 ) at 50

27.1 (4.5)

26.6 (4.4)

27.6 (5.2)

0.038

0.026

0.629

  1. *indicate P values calculated assuming additive, dominant, and recessive models. P values <0.05 are highlighted in bold case.