From: Physical growth, puberty and hormones in adolescents with Nodding Syndrome; a pilot study
ID | Age in years, gender | Duration of signs in years | Main clinical features | WAZ score | HAZ score | Tanner stage (Breast/Testis) | Bone Age (years) | Vit D(ng/ml) | IGF1(ng/ml) | IGFBP3(μg/ml) |
---|---|---|---|---|---|---|---|---|---|---|
1 | 15, Male | 8 | Head nodding only; Frequent head nods, triggered by food; has difficulties in speech | - 4.75 | -4.04 | 2 | 10 | 21.3 | 157 | 2.8 |
2 | 14, Female | 9 | Head nodding only; head nods triggered by food or appearing spontaneously. Three siblings and cousins also have NS. | -1.85 | -1.49 | 2 | 12 | 23.0 | 286 | 4.3 |
3 | 13, Male | 8 | Head nodding plus; Head nods appear spontaneously; Frequent hallucinations | -1.53 | -2.63 | 1 | 9 | 21.9 | 295 | 4.1 |
4 | 15, Female | 9 | Head nodding plus; head nods triggered by food and cold weather. Aggressive behaviour and often disoriented. | -5.05 | -3.07 | 2 | Not done | 33.7 | 216 | 3.8 |
5 | 18, Female | 8 | Head nodding plus; head nods triggered by food; periods of being aggressive; visual hallucinations | -1.11 | -0.10 | 3 | 17 | 25.2 | 231 | 3.4 |
6 | 14, Female | 5 | Head nodding only; head nods triggered by food; 3 other siblings also have nodding syndrome. | -1.42 | -1.78 | 2 | 12 | 25.8 | 332 | 4.6 |
7 | 13, Female | 6 | Head nodding plus; head nods are spontaneous; Severe burn injury with a submental fistula | -3.17 | -2.62 | 2 | 10 | 19.3 | 268 | 3.9 |
8 | 13, Female | 6 | Head nodding plus; Head nods triggered by food and occur spontaneously. Severe and uncontrolled seizures, behavior difficulties and psychotic behavior | -3.22 | -2.23 | 1 | 10 | 18.8 | 164 | 3.8 |
9** | 15, Male | 2 | Head nodding only | -3.25 | -3.05 | 1 | Not done | 34.6 | No result | No result |