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Table 2 Treatment schedule and dosage of sunitinib, and efficacy

From: Efficacy and tolerability of a low-dose, 2-week administration of sunitinib followed by a week rest (2/1 schedule) for metastatic renal cell carcinoma: a single center experience of six cases

No. Dosage Schedule Duration of use Response PFS
1 37.5 mg 4 weeks on/2 weeks off 1 month PR 19 months
25 mg 4 weeks on/2 weeks off 2 months   
25 mg 2 weeks on/1 week off 21 months   
2 37.5 mg 4 weeks on/2 weeks off 1 month SD 9 months
25 mg 4 weeks on/2 weeks off 2 months   
25 mg 2 weeks on/1 week off 6 months   
3 37.5 mg 4 weeks on/2 weeks off 1 month PR 17 months
25 mg 2 weeks on/1 week off 26 months   
4 37.5 mg 4 weeks on/2 weeks off 1 month PR 13 months
25 mg 4 weeks on/2 weeks off 3 months   
25 mg 2 weeks on/1 week off 9 months   
5 37.5 mg 4 weeks on/2 weeks off 1 month PR 38 months
25 mg 3 weeks on/1 week off 22 months   
25 mg 2 weeks on/1 week off 17 months   
6 37.5 mg 4 weeks on/2 weeks off 1 month PR 23 months
25 mg 4 weeks on/2 weeks off 5 months   
  25 mg 2 weeks on/1 week off 18 months   
  1. PR, partial response; SD, stable disease.
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BMC Research Notes

ISSN: 1756-0500

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