Amino acid positions of the LRR XII kinase domain subject to non-synonymous nucleotide variations. Sequences of phylogenetic clades of LRR XII(−L) of Pac and LRR XII of Arabidopsis were included in the analysis. Positions subject to non-synonymous variations are shaded black. Sequences in the alignment are representatives of each group. Long arrows show non-synonymous positions shared among all sequence groups. Short dotted arrows show non-synonymous positions shared among three groups of sequences. Stars above the alignments show non-synonymous positions that are exclusive to a single group of sequences. The invariant residues of the kinase superfamily (from III to IX) are in bold and shaded grey. The brackets indicate the regions where purifying selection is more relaxed, based on the analysis presented in Figure 7.