Association between hTERT polymorphisms and the risk of breast cancer in a sample of Southeast Iranian population

Table 4 Association between hTERT polymorphisms and clinicopathological characteristics

Variables	MNS16A			p	rs2735940			p	rs2736098			p
	LL	LS	SS		CC	CT	TT		AA	AG	GG
Age (years)				0.123				0.181				0.893
≤50	58	83	7		21	70	57		21	82	39
>50	56	48	7		24	52	33		17	57	30
Pathological type				0.812				0.704
Ductal	78	87	10		30	85	60		30	91	45	0.351
Others	37	49	5		15	39	35		10	49	28
Tumor size (cm)				0.429				0.427				0.575
≤2	35	47	6		12	44	32		14	48	19
>2	77	79	7		33	76	54		22	89	46
TNM Stage				0.850				0.237				0.595
I	19	22	3		7	25	12		8	27	8
II	47	48	5		19	41	40		12	51	32
III	32	35	3		14	38	17		12	37	17
IV	13	24	2		5	17	17		4	21	11
Grade				0.437				0.072				0.286
I	23	21	2		10	19	17		10	20	14
II	64	67	7		18	62	58		17	81	34
III	14	30	1		11	26	8		6	22	15
IV	0	0	0		0	1	0		0	0	0
ER status				0.858				0.090				0.260
Positive	68	78	8		26	81	47		23	79	46
Negative	37	43	3		15	32	36		14	47	16
PgR status				0.627				0.620				0.137
Positive	62	79	6		28	71	48		18	80	42
Negative	41	42	5		13	42	33		19	44	20
HER2 status				0.155				0.404				0.186
Positive	50	69	9		27	59	42		15	75	32
Negative	61	59	4		18	60	45		22	59	36

ISSN: 1756-0500