Experimental validation of predicted subcellular localizations of human proteins

BMC Research Notes

Table 2 Experimental validation of ngLOC top second predicted proteins subcellular localization

Protein	First Prediction	Second Prediction	Validation for First prediction	Validation for Second prediction
U2AF1L4	NUC	CYT	*	*
CARD17	CYT	NUC	*	*
RAC1	CYT	PLA	No	No
PCTP	CYT	NUC	*	*
PEBP1	CYT	PLA	No	No
RPL36AL	CYT	NUC	*	*
GST5A	CYT	NUC	*	*
PCMT	CYT	NUC	*	*
PGPEP1	CYT	NUC	*	*
PMP2	CYT	NUC	*	*
PPIAL4A	CYT	MIT	No	Yes
GABRAPL2	GOL	CSK	No	Yes
MRPL51	MIT	CYT	No	No
MRPL53	MIT	CYT	No	No
DYNLL2	CSK	NUC	*	*
TMSB4Y	CSK	CYT	*	*
TMSB15A	CSK	NUC	*	*
PXMP4	POX	PLA	Yes	No
MMD	LYS	PLA	Yes	No
RAB7A	LYS	PLA	Yes	No
SEC61G	END	MIT	Yes	Yes
DGAT2	END	PLA	Yes	No
DOLPP1	END	PLA	Yes	Yes
SEC11A	END	PLA	Yes	No
CNPY3	END	PLA	Yes	No
LMO1	NUC	MIT	Yes	Yes
LMO2	NUC	PLA	Yes	Yes
NUDT10	CYT	PLA	Yes	No
CDC42EP5	CSK	PLA	Yes	Yes
ZDHHC3	GOL	PLA	Yes	Yes

The asterisk (*) represents homogenous distribution where localization of protein was seen in both cytoplasm and nucleus.

ISSN: 1756-0500