From: Mediation analysis of gestational age, congenital heart defects, and infant birth-weight
Variable | Parameter estimate | Standard error | t–value | p–value |
---|---|---|---|---|
(a) Model 1 (dependent variable is birth weight in grams) | ||||
 Intercept | 3349.39 | 14.82 | 226.07 | <0.0001 |
 CHD1 | −279.00 | 15.82 | −17.64 | <0.0001 |
 Child’s sex2 | 137.53 | 15.81 | 8.70 | <0.0001 |
 1–10 cigarettes/day3 | −191.44 | 22.14 | −8.64 | <0.0001 |
 11–20 cigarettes/day3 | −167.19 | 22.96 | −7.28 | <0.0001 |
 21–39 cigarettes/day3 | −224.75 | 40.60 | −5.54 | <0.0001 |
 40 or more cigarettes/day3 | −240.76 | 68.92 | −3.49 | 0.0005 |
(b) Model 2 (dependent variable is gestational age in weeks) | ||||
 Intercept | 39.64 | 0.06 | 708.67 | <0.0001 |
 CHD1 | −0.69 | 0.06 | −11.54 | <0.0001 |
 Child’s sex2 | 0.04 | 0.06 | 0.64 | 0.5198 |
 1–10 cigarettes/day3 | −0.26 | 0.08 | −3.16 | 0.0016 |
 11–20 cigarettes/day3 | −0.21 | 0.09 | −2.46 | 0.0138 |
 21–39 cigarettes/day3 | −0.21 | 0.15 | −1.38 | 0.1662 |
 40 or more cigarettes/day3 | −0.07 | 0.26 | −0.27 | 0.7880 |
(c) Model 3 (dependent variable is birth weight in grams) | ||||
 Intercept | −3157.30 | 99.75 | −31.65 | <0.0001 |
 Gestational age | 164.13 | 2.50 | 65.68 | <0.0001 |
 CHD1 | −165.92 | 12.53 | −13.24 | <0.0001 |
 Child’s sex2 | 131.23 | 12.41 | 10.57 | <0.0001 |
 1–10 cigarettes/day3 | −148.04 | 17.39 | −8.51 | <0.0001 |
 11–20 cigarettes/day3 | −132.14 | 18.03 | −7.33 | <0.0001 |
 21–39 cigarettes/day3 | −189.91 | 31.87 | −5.96 | <0.0001 |
 40 or more cigarettes/day3 | −229.28 | 54.09 | −4.24 | <0.0001 |