Table 3 Point estimates and 95% confidence intervals (CI) of the mediated effect and mediation proportion using three approaches
From: Mediation analysis of gestational age, congenital heart defects, and infant birth-weight
(a). MEDIATED EFFECT | |||
Estimation method | Wald statistic method | Likelihood-based method | Bootstrap method |
Estimate (95% CI) | 113.08 (93.6–132.6) | 113.08 (99.9–117.8) | 113.51 (92.4–134.2) |
(b). MEDIATION PROPORTION | |||
Estimation method | The delta method | Fieller’s method | Bootstrap method |
Estimate (95% CI) | 40.5% (32.2%–48.8%) | 40.5% (35.2%–45.9%) | 40.7% (34.7%–46.6%) |