Table 2 Characteristics of S. sonnei isolates from Bhutan, Nepal and Thailand
Study site | Number of isolates | Resistance pattern | MIC (μg/ml) | Integrons | DNA Gyrase A mutation | Replicon plasmid | |||
|---|---|---|---|---|---|---|---|---|---|
AZM | NA | CIP | Ser83 | Asp87 | |||||
Bhutan | 19 | S, SXT, TE, NA, CIP | 3.0-4.0 | >256 | 3.0-4.0 | Class 2 | Ser83Leu | Asp87Gly | ColE |
Bhutan | 9 | S, SXT, TE, NA, CIP | 3.0-4.0 | >256 | 3.0-4.0 | Class 2 | Ser83Leu | Asp87Gly | B/O, ColE |
Bhutan | 1 | S, SXT, TE, NA, CIP | 4.0 | >256 | 3.0 | Class 2 | Ser83Leu | Asp87Gly | I1, ColE |
Nepal | 1 | S, SXT, TE, NA, CIP | 4.0 | >256 | 4.0 | Class 2 | Ser83Leu | Asp87Gly | ColE |
Nepal | 2 | S, SXT, TE, NA | 3.0-4.0 | >256 | 0.190-0.125 | Class 2 | Ser83Leu | Neg | ColE |
Nepal | 1 | S | 3.0 | 3.0 | 0.008 | Neg | Neg | Neg | ColE |
Thailand | 1 | S, SXT, TE, NA, AM | 3.0 | >256 | 0.190 | Neg | Ser83Leu | Neg | B/O, ColE |
Thailand | 1 | S, SXT, TE, AM | 3.0 | 3.0 | 0.004 | Neg | Neg | Neg | I1, ColE |
Thailand | 2 | S, SXT, TE, NA, AM | 3.0-4.0 | 128 | 0.004 | Class 2 | Neg | Asp87Tyr | I1, ColE |
Thailand | 1 | S, SXT, TE, NA, | 4.0 | >256 | 0.004 | Class 2 | Ser83Leu | Neg | ColE |