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Table 2 Amino acid similarity among the HA proteins of different H1N1pdm isolates, compared with A/California/07/2009

From: Amino acid substitutions in hemagglutinin of the 2009 pandemic influenza A(H1N1) viruses that might affect the viral antigenicity

Region Number of amino acids involved (position) Number of amino acid residues identical to A/CA/07/2009 (H1N1) (amino acid substitution position)
Thai/104 CBI6 CBI10 34002 34004 NMA1 BKK1 BKK2 BKK4 BKK5
HA1 globular head 234 (42-275) 233 (P83S) 232 (P83S) 230 (P83S) (K119E) 231 (P83S) (S128L) 232 (P83S) 232 (P83S) 228 (P83S) (D97N) (I216V) (V249L) 228 (P83S) (D97N) (I216V) (V249L) 227 (P83S) (D97N) (K119N)* (V249L) 227 (P83S) (D97N) (N129D) (V249L)
Sa 13 13 13 13 13 13 13 13 13 13 13
Sb 12 12 12 12 12 12 12 12 12 11 (S185T) 11 (S185T)
Ca 19 19 18 (S203T) 17 (S203T) (D222G) 18 (S203T) 18 (S203T) 18 (S203T) 17 (S203T) (R205K) 17 (S203T) (R205K) 17 (H138R) (S203T) 17 (H138R) (S203T)
Cb 6 6 6 6 6 6 6 6 6 6 6
HA2 222 (328-549) 221 (I404M) 222 222 221 (E374K) 221 (E374K) 221 (E374K) 221 (E374K) 221 (E374K) 220 (E374K) (S451N) 220 (E374K) (S451N)
  1. 17 amino acids of the signal peptide starting from M are not included. The first HA position starts from D.
  2. Amino acid residues in Sa, Sb, Ca, and Cb sites of the globular head are defined according to reference [10].
  3. *Substitution point affecting glycosylation.