Skip to main content

Table 2 Amino acid similarity among the HA proteins of different H1N1pdm isolates, compared with A/California/07/2009

From: Amino acid substitutions in hemagglutinin of the 2009 pandemic influenza A(H1N1) viruses that might affect the viral antigenicity

Region

Number of amino acids involved (position)

Number of amino acid residues identical to A/CA/07/2009 (H1N1) (amino acid substitution position)

Thai/104

CBI6

CBI10

34002

34004

NMA1

BKK1

BKK2

BKK4

BKK5

HA1 globular head

234 (42-275)

233 (P83S)

232 (P83S)

230 (P83S) (K119E)

231 (P83S) (S128L)

232 (P83S)

232 (P83S)

228 (P83S) (D97N) (I216V) (V249L)

228 (P83S) (D97N) (I216V) (V249L)

227 (P83S) (D97N) (K119N)* (V249L)

227 (P83S) (D97N) (N129D) (V249L)

Sa

13

13

13

13

13

13

13

13

13

13

13

Sb

12

12

12

12

12

12

12

12

12

11 (S185T)

11 (S185T)

Ca

19

19

18 (S203T)

17 (S203T) (D222G)

18 (S203T)

18 (S203T)

18 (S203T)

17 (S203T) (R205K)

17 (S203T) (R205K)

17 (H138R) (S203T)

17 (H138R) (S203T)

Cb

6

6

6

6

6

6

6

6

6

6

6

HA2

222 (328-549)

221 (I404M)

222

222

221 (E374K)

221 (E374K)

221 (E374K)

221 (E374K)

221 (E374K)

220 (E374K) (S451N)

220 (E374K) (S451N)

  1. 17 amino acids of the signal peptide starting from M are not included. The first HA position starts from D.
  2. Amino acid residues in Sa, Sb, Ca, and Cb sites of the globular head are defined according to reference [10].
  3. *Substitution point affecting glycosylation.