From: Vitamin D supplementation in children with asthma: a systematic review and meta-analysis
Vitamin D compared to No vitamin D for children with asthma | |||
---|---|---|---|
Outcomes | No of participants (studies) follow up | Quality of the evidence (GRADE) | Anticipated effects |
Asthma related symptoms | 116 | ⊕⊝⊝⊝ | Heterogeneous and not definitive data, not pooled |
Different instruments/scales | (3 studies) | VERY LOW 1,2,3 | |
1.5-12 months | due to risk of bias, heterogeneity, imprecision | ||
FEV1 | 82 | ⊕ ⊕ ⊝⊝ | The mean FEV1 in the intervention groups was |
(2 studies) | LOW 3,4,5 | 0.54 lower (5.28 lower to 4.19 higher) | |
6-12 months | due to risk of bias, imprecision | ||
Vitamin D levels | 116 | ⊕⊝⊝⊝ | The mean vitamin D levels in the intervention groups was |
(3 studies) | VERY LOW 1,6,7 | 6.6 higher (0.6 lower to 13.8 higher) | |
1.5-6 months | due to risk of bias, heterogeneity, imprecision |