Table 9 Multivariate analysis of melanoma-specific survival

Gender

Male

188

1.000

-

Female

221

0.508

0.314; 0.822

0.006

Age

-

409

1.005

0.988; 1.021

0.582

DHL

-

409

1.003

1.001; 1.004

Anatomical location

Head and neck

75

1.000

-

Lower limbs

126

0.575

0.305; 1.084

0.087

Upper limbs

61

0.398

0.181; 0.878

0.022

Trunk

147

0.429

0.226; 0.814

0.010

Histological subtype

Acral lentiginous

30

1.000

-

Nodular

149

0.777

0.368; 1.642

0.509

Superficial spreading

190

0.889

0.399; 1.981

0.774

Lentigo maligna

14

0.516

0.098; 2.702

0.433

Not classified/other

26

0.305

0.077; 1.207

0.091

Ulceration

Present

167

1.000

-

Absent

242

0.902

0.554; 1.468

0.678

T

T1

105

1.000

-

T2

104

3.005

1.135; 7.957

0.027

T3

84

2.502

0.862; 7.264

0.092

T4

116

4.264

1.479; 12.293

0.007

N

N0

310

1.000

-

N1

34

2.143

1.058; 4.340

0.034

N2

31

2.163

1.072; 4.367

0.031

N3

34

3.249

1.772; 5.954

M

M0

395

1.000

-

M1

14

3.658

1.633; 8.192

0.002

Locoregional recurrence

No

367

1.000

-

Yes

42

2.198

1.307; 3.696

0.003