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Table 2 Expression of Chr3 genes near the Sry transgene

From: Four Core Genotypes mouse model: localization of the Sry transgene and bioassay for testicular hormone levels

 

FCG

WT

Distance

Probe

ANOVA

FDR

MF

ANOVA

FDR

MF

(bp)

Lxn

0.001

0.035

-0.08

0.549

0.998

0.02

-3215751

Rarres1

0.868

0.963

-0.01

0.678

0.999

-0.02

-3194863

Mfsd1

0.187

0.530

-0.04

0.339

0.951

-0.05

-3090981

Schip1

0.033

0.225

-0.04

0.806

0.999

-0.01

-2608947

Schip1

0.568

0.837

-0.01

0.615

0.999

 

-2608947

Il12a

0.310

0.656

-0.01

0.598

0.999

0.01

-1983105

Trim59

0.021

0.179

-0.09

0.160

0.832

0.03

-1638461

Trim59

0.950

0.985

0.00

0.623

0.999

0.02

-1638461

Kpna4

0.868

0.963

0.00

0.760

0.999

-0.01

-1606600

Ppm1l

0.034

0.230

0.08

0.002

0.417

0.06

-1356888

Nmd3

0.085

0.362

0.07

0.083

0.734

0.10

-951764

Sry transgene

      

0

Slitrk3

0.346

0.684

-0.02

0.728

0.999

0.02

2374377

Bche

0.060

0.306

0.10

0.931

0.999

-0.01

2962059

Serpini2

0.676

0.890

0.01

0.942

0.999

0.00

4568621

Pdcd10

0.231

0.580

0.03

0.308

0.938

0.04

4842741

Pdcd10

0.336

0.677

0.02

0.278

0.926

0.04

4842741

Serpini1

0.130

0.447

0.01

0.509

0.993

-0.02

4883798

Fstl5

0.917

0.978

0.00

0.831

0.999

0.01

5400521

Rapgef2

0.900

0.973

0.00

0.319

0.946

0.03

8388767

Ppid

0.002

0.056

0.14

0.674

0.999

0.02

8917593

Etfdh

0.024

0.191

0.09

0.987

0.999

0.00

8930039

4930579G24Rik

0.658

0.880

0.02

0.118

0.776

-0.07

8955330

  1. The table shows ANOVA and False Discovery Rate (FDR) p-values of Sry effects on gene expression in liver of FCG mice (effect of Sry transgene) and of WT mice (effect of endogenous Sry). For several genes, p values for two different probes for the same gene are shown. MF is fractional mean difference between males (M, with Sry) and females (F, without Sry). For example, -0.08 means that F had about 8% higher expression than M. Distance is relative to the Sry transgene in FCG mice.