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Table 2 The coefficient of determination (r 2 ) of the four cytotoxicity assays

From: Limitations of the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay when compared to three commonly used cell enumeration assays

Cell lines and incubation periods NRU MTT RES SRB
MCF-7 24 hours incubation 0.901 0.711 0.999 0.992
MDA-MB-231 0.979 0.975 0.998 0.999
MCF-12A 0.846 0.903 0.976 0.999
MCF-7 72 hours incubation 0.994 0.762 0.915 0.999
MDA-MB-231 0.958 0.878 0.843 0.973
MCF-12A 0.986 0.990 0.887 0.985
Average 0.937 0.864 0.934 0.991
  1. The neutral red, MTT, resazurin reduction and SRB assays were performed after 24 or 72 hour incubation on three cell lines (n = 4).
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