Skip to main content

Table 4 Area at risk (AAR) by field strength and quantification method and corresponding reproducibilities

From: Comparison of semi-automated methods to quantify infarct size and area at risk by cardiovascular magnetic resonance imaging at 1.5T and 3.0T field strengths

  

1.5T

  

3.0T

 
 

AAR (2SD)

AAR (OAT)

AAR (MANUAL)

AAR (2SD)

AAR (OAT)

AAR (MANUAL)

Mean value (AAR [% LVM])

34.8 ± 9.8

38.1 ± 13.0

35.4 ± 11.2

35.2 ± 14.4

38.9 ± 9.9a

30.0 ± 8.2

ICC v Manual

0.865

0.920

 

0.649

0.465

 

Mean bias v Manual (±1.96SD LoA)

+0.31 (+12.20, −11.57)

+3.62 (+11.24, −4.00)

 

+5.13 (+22.76, −12.50)

+8.92 (+23.15, −5.31)

 

Interobserver ICC

0.908

0.976

0.825

0.869

0.981

0.716

Interobserver mean bias (±1.96SD LoA)

+3.38 (+9.12, −2.37)

+1.26 (+7.20, −4.68)

+1.31 (+17.11, −14.49)

−0.34 (+15.36, −16.03)

−1.35 (+1.64, −4.33)

−5.20 (+9.54, −19.95)

Intraobserver ICC

0.948

0.995

0.977

0.987

0.990

0.826

Intraobserver mean bias (±1.96SD LoA)

+2.80 (+7.28, −1.68)

+0.58 (+3.31, −2.16)

−0.01 (+5.62, −5.64)

+1.00 (+5.50, −3.51)

+0.04 (+2.82, −2.74)

+1.46 (+14.84, −11.93)

  1. AAR and MSI expressed as mean ± standard deviation. 2SD = >2 standard deviations, OAT = Otsu’s Automated Thresholding, LVM = Left Ventricular Mass, ICC = Intraclass Correlation Coefficient, LoA = Limits of Agreement (Bland-Altman).
  2. a - p < 0.05 vs. manually quantified AAR.