Differences in IL-10 serum levels according to infection status of the study population (
= 39). Children were enrolled in primary schools located in rural seven communities of the Department of Olancho, Honduras. A) Comparison of serum IL-10 levels in non-parasitized children and children parasitized with one or more species of soil-transmitted helminths as detected with the Kato-Katz method (Ascaris lumbricoides, Trichuris trichiura, and hookworms). Children infected with any of the three STH species investigated had higher IL-10 levels than non-parasitized children (geometric means: 0.89 pg/mL vs. 0.74 pg/mL p = 0.428). Statistical comparisons were conducted using Mann–Whitney U test (Wilcoxon rank-sum). B) Comparison of serum IL-10 levels in non-parasitized, monoparasitized (infection with a single species) and polyparasitized children (infection with 2 or more species). Polyparasitized children had higher IL-10 levels than both non-parasitized and monoparasitized children (1.04 pg/mL, 0.74 pg/mL and 0.69 pg/mL, respectively, p = 0.481). Statistical comparisons were conducted using Kruskal-Wallis rank test. Boxplots show median values (horizontal center line), inter-quartile range (box margins), and 95% confidence intervals (bars).