Figure 3

Demonstration of advanced search. (A) Results from a search for genes with hsa-mir-106a as miRNA regulator (without restrictions on verification status or number of regulators). (B) Network generated from the same search, showing hsa-mir-106a (yellow triangle), four of its target genes (green nodes) and other miRNAs targeting these genes (pink nodes). Triangles indicate up-regulation in cancer, V shapes indicate down-regulation and squares indicate that there is no experimental data on expression in EC. Edges indicate gene-miRNA relationships, with thick black edges indicating verified regulation. The network can be downloaded using the SIF hyperlink under the heading Human Graph above the results table in Figure 3A.