Heatmaps of gene expression, copy number variation (CNV), and methylation level of the 505 differentially expressed genes in tumor tissue. In the gene expression heatmap (middle column), red represents up-regulation and green represents down-regulation. The gene order was the same in all three panels. For CNV and methylation alteration (left, right columns), one-way hierarchical clustering was first performed on the β-value difference and subsequently the copy number difference. For CNV (left column), gold indicates amplification and cyan indicates deletion. For methylation level (right column), blue denotes hypermethylation and yellow denotes hypomethylation.