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Table 1 Titers of antibodies against A/H1N1 influenza in volunteers of different ages examined in 2010

From: Serum strain-specific or cross-reactive neuraminidase inhibiting antibodies against pandemic А/California/07/2009(H1N1) influenza in healthy volunteers

Groups

Year of birth

Antibodies against H1N1/2009pdm, log2

Antibodies against H1N1/1999, log2

HI titers, Me (Q1;Q3)

NI titers, Me (Q1;Q3)

HI titers, Me (Q1;Q3)

NI titers, Me (Q1;Q3)

1 (n = 24)

Before 1957

2.31 (2.3;2.3)

3.5 (2.3;5.3)

2.32 (2.3;2.8)

3.9 (2.3;5.1)

2 (n = 24)

1957–1976

2.3 (2.3;5.3)

2.33 (2.3;3.3)

2.3 (2.3;4.3)

3.8 (2.3;4.6)

3 (n = 78)

1977–1999

4.34 (3.3;5.3)

4.3 (3.4;5.3)

6.35 (5.3;8.3)

5.76 (4.8;6.4)

4 (n = 37)

After 2000

2.3 (2.3;5.3)

2.9 (2.3;5.3)

2.3 (2.3;5.3)

3.4 (2.3;5.3)

  1. Key: Me (medians), Q1; Q3 (lower and upper quartiles).
  2. 1Mean titers of HI antibodies against H1N1/2009pdm are lower than NI antibodies (p = 0.001).
  3. 2Mean titers of HI antibodies against H1N1/1999 are lower than NI antibodies (p = 0.006).
  4. 3Mean titers of antibodies against NA of pandemic influenza virus H1N1/2009pdm in are lower in group 2 than in group 3 (p = 0.002).
  5. 4Mean titers of HI antibodies against H1N1/2009pdm are higher in group 3 than in group 1 (p = 0.0002).
  6. 5Mean titers of HI antibodies against H1N1/1999 are higher in group 3 than in groups 1, 2, and 4 (p < 0.0001).
  7. 6Mean titers of NI antibodies H1N1/1999 are higher in group 3 than in groups 1, 2, and 4 (p < 0.001).