Table 4 Common physiochemical parameters identified for COX-1, COX-2, 5-LOX, 12-LOX and 15-LOX
15-LOX | 12-LOX | 5-LOX | COX-1 | COX-2 | |||||
|---|---|---|---|---|---|---|---|---|---|
A. A. | Type | A. A. | Type | A. A. | Type | A. A. | Type | A. A. | Type |
Glu 357 | ACC | Glu 356 | ACC | Gln 363 | ACC | Ser 530 | DAC | Ser 530 | DAC |
His 361 | DAC | His 360 | DAC | His 367 | DAC | Ala 527 | DON | Ala 527 | DON |
His 361 | PII | His 360 | PII | His 367 | PII | Gly 526 | PII | Gly 526 | PII |
Leu 362 | ALI | Leu 361 | ALI | Leu 368 | ALI | Met 522 | ALI | Met 522 | ALI |
Leu 408 | ALI | Val190 | ALI | Ile 415 | ALI | Leu 352 | ALI | Leu 352 | ALI |