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Table 1 Summary of Gene Ontology (GO) biological processes over-represented in the PMT70 data (p < 0.01, FWFDR < 0.10)

From: Transcriptional profiling of PRKG2-null growth plate identifies putative down-stream targets of PRKG2

GO ID and Term

# genes

% total

P-value

Benjamini *

GO:0048468 ~ cell development

82

10.26%

0.0001

0.02

GO:0048856 ~ anatomical structure development

127

15.89%

0.0002

0.02

GO:0043170 ~ macromolecule metabolic process

357

44.68%

0.0004

0.02

GO:0016043 ~ cellular component organization and biogenesis

153

19.15%

0.0004

0.02

GO:0008283 ~ cell proliferation

56

7.01%

0.0004

0.01

GO:0044238 ~ primary metabolic process

400

50.06%

0.0010

0.03

GO:0044237 ~ cellular metabolic process

399

49.94%

0.0010

0.02

GO:0019953 ~ sexual reproduction

28

3.50%

0.0011

0.02

GO:0007275 ~ multicellular organismal development

132

16.52%

0.0011

0.02

GO:0048869 ~ cellular developmental process

107

13.39%

0.0011

0.02

GO:0006928 ~ cell motility

32

4.01%

0.0030

0.04

GO:0051674 ~ localization of cell

32

4.01%

0.0030

0.04

GO:0009566 ~ fertilization

9

1.13%

0.0042

0.05

GO:0016265 ~ death

53

6.63%

0.0053

0.06

GO:0009605 ~ response to external stimulus

43

5.38%

0.0056

0.06

GO:0007049 ~ cell cycle

56

7.01%

0.0056

0.06

GO:0006950 ~ response to stress

65

8.14%

0.0067

0.06

GO:0022414 ~ reproductive process

24

3.00%

0.0073

0.06

  1. *Benjamini is a measure of family-wise false discovery rate as described by Huang da et al. [13].