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Table 2 Summary of Panther molecular function categories over-represented in the PMT70 data (p < 0.01, FWFDR < 0.10)

From: Transcriptional profiling of PRKG2-null growth plate identifies putative down-stream targets of PRKG2

Panther molecular function process

# genes

% total

P-value

Benjamini *

MF00213: Non-receptor serine/threonine protein kinase

188

23.5

6.00E-10

1.40E-07

MF00042: Nucleic acid binding

299

37.4

7.40E-09

8.80E-07

MF00131: Transferase

113

14.1

1.50E-08

1.20E-06

MF00108: Protein kinase

75

9.4

1.30E-04

6.00E-03

MF00262: Non-motor actin binding protein

137

17.1

2.80E-04

1.10E-02

MF00101: Guanyl-nucleotide exchange factor

98

12.3

7.50E-03

9.00E-02

  1. *Benjamini is a measure of family-wise false discovery rate as described by Huang da et al. [13].