Dysregulated mechanisms underlying Duchenne muscular dystrophy from co-expression network preservation analysis

BMC Research Notes

Table 1 Enrichment of modules identified in the healthy network

Module	#Nodes	Top Term	p value
N1	590	striated muscle contraction	7.59E-07
N2	323	extracellular structure organization	2.90E-08
N3	109	actin cytoskeleton organization	1.50E-02
N4	598	modification-dependent macromolecule catabolic process	2.36E-04
N5	349	intracellular protein transport	7.69E-06
N6	93	generation of precursor metabolites and energy	8.27E-39
N7	215	chromatin assembly or disassembly	8.06E-04
N8	125	muscle organ development	3.74E-03
N9	171	fatty acid metabolic process	3.85E-05
N10	1102	intracellular protein transport	5.12E-05
N11	319	ribosomal small subunit biogenesis	4.28E-05

This table represents the top functional enrichment term from the highest ranking annotation cluster identified for each module of the healthy network. The annotation clusters were ranked and identified using DAVID’s annotation clustering tool [31] [see Additional file 6].

ISSN: 1756-0500