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Table 1 Vaccination scenarios to be examined using the dynamic model

From: Early vaccine availability represents an important public health advance for the control of pandemic influenza

 

Scenarios 1 and 2

Scenarios 3 and 4

Scenarios 5 and 6

Pandemic transmissibility*

Mild/Severe

Mild/Severe

Mild/Severe

Season of emergence

Spring/Fall

Spring/Fall

Spring/Fall

Level of pre-existing immunity in level of pre-existing immunity in population

0%

0%

0%

Time at which first vaccine becomes available (range)

6 months

1 month (1–3 months)

1 month (1–3 months)

Time at which additional vaccine becomes available

_

_

6 months

Doses of traditional (egg-based) vaccine required

1/2

_

1/2

Doses of novel (plant-based) vaccine required

_

1/2

1/2

Vaccine coverage*

UIIP

UIIP

UIIP

Vaccine production for traditional vaccine

3.75 M doses/week

 

3.75 M doses/week

Vaccine production for novel vaccine

 

150,000 doses/week1.5 M doses/week

150,000 doses/week1.5 M doses/week

Outcomes**

CPIP moderate

CPIP moderate

CPIP moderate

  1. *See Table 2 for details regarding specific parameter values for pandemic influenza transmissibility scenarios and vaccine coverage.
  2. **See Table 2 for details.