Changes in nine hematological parameters in mock-treated and infected DBA/2J and C57BL/6J mice. Data points were collected across the 5-day time course of IAV infection. Panels show mean values and variation of the data (standard deviation) of WBC (a, b), LYM (c, d), MON (e, f), GRA (g, h), LYM% (i, j), MON% (k, l), GRA% (m, n), PLT (o, p), and GRA/LYM ratio (q, r). Horizontal black lines indicate values of untreated mice (t = 0 h). Left panel results obtained with the DBA/2J mouse strain. Right panel results obtained with the C57BL/6J mouse strain. Solid lines mice infected with 2 × 103 ffu IAV PR8 M in 20 µl sterile PBS. Interrupted lines mice undergoing the same anesthesia/infection procedure except that buffer only, not containing IAV, was used for the intranasal installation (“mock treatment”). *p ≤ 0.05 for difference between infected mice at the given time point with respect to 0 h; ∆p ≤ 0.05 for difference between mock treated and control (0 h) mice; ‡p ≤ 0.05 for difference between infected and mock treated mice at the given time point. All p values were determined with Tukey’s test.