Principal component analysis of eight hematological parameters across the 5-day time course of IAV infection. The parameters WBC, LYM, MON, GRA, LYM%, MON%, GRA%, and PLT were measured in mock-treated and infected DBA/2J and C57BL/6J mice at 6, 12, 18, 24, 48, and 120 h, as well as in untreated mice (0 h). The analysis is based on the same data set as used for Figure 2. Each dot refers to the mean value of mice of one treatment as outlined in the legend adjacent to the box. The number inside each dot identifies the time (h) elapsed since 0 h. Including the GRA/LYM ratio or the third component did not improve discrimination (data not shown).