Table 2 The estimated substitution rates and the dates of most recent common ancestor by four different models
From: Genetic characterization of measles virus in the Philippines, 2008–2011
Molecular clock | Demographic model | Substitution ratea, ×10−3 (95% HPD) | tMRCA, D9 (95% HPD) | tMRCA, G3 (95% HPD) |
|---|---|---|---|---|
Strict | Constant | 2.54 (0.96–4.35) | 2005 September 20 (2002 May to 2007 Nov) | 2008 May 18 (2007 Oct to 2008 Aug) |
Strict | Exponential growth | 2.71 (1.10–4.47) | 2006 January 12 (2003 Mar to 2007 Nov) | 2008 May 29 (2007 Nov to 2008 Aug) |
Lognormal relaxed | Constant | 2.78 (0.72–4.96) | 2005 August 3 (2001 Sept to 2007 Nov) | 2008 May 15 (2007 Sept to 2008 Aug) |
Lognormal relaxed | Exponential growth | 3.37 (0.92–6.23) | 2006 January 20 (2003 Jan to 2007 Nov) | 2008 May 24 (2007 Oct to 2008 Aug) |