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Table 5 Classification of structural elements, specific to each modelling approach, according to the decision frameworks

From: Systematic narrative review of decision frameworks to select the appropriate modelling approaches for health economic evaluations

Modelling approach Number of frameworks that include this modelling approach
n (%a)
Structural assumptions n (%b) [reference]
Population resolution First-order uncertainty Interactivity Resource constraints Dimension of time
Not specified within framework Classification Not specified within framework Classification Not specified within framework Classification Not specified within framework Classification Not specified within framework Classification
Cohort Individual Deterministic Stochastic Static/independent Dynamic/dependent Unlimited resources Constrained resources Untimed Discrete Continuous
Decision tree 8 (100) 3 (37.5)
[6, 9, 12]
5 (62.5)
[7, 8, 10, 11, 13]
3 (37.5)
[10, 11, 13]
4 (50)
[6, 9, 12, 13]
4 (50)
[7, 8, 10, 11]
2 (25)
[10, 11]
2 (25)
[7, 11]
6 (75)
[6, 810, 12, 13]
0 6 (75)
[6, 811, 13]
2 (25)
[7, 12]
0 4 (50)
[6, 8, 9, 12]
4 (50)
[7, 10, 11, 13]
0 0
Markov cohort model 8 (100) 3 (37.5)
[6, 9, 12]
5 (62.5)
[7, 8, 10, 11, 13]
0 4 (50)
[6, 9, 12, 13]
3 (37.5)
[7, 8, 10]
2 (25)
[10, 11]
2 (25)
[7, 11]
6 (75)
[6, 810, 12, 13]
0 6 (75)
[6, 811, 13]
2 (25)
[7, 12]
0 4 (50)
[6, 8, 9, 12]
0 4 (50)
[7, 10, 11, 13]
1 (12.5)
[13]
Microsimulation 6 (75) 1 (16.6)
[9]
0 5 (83.3)
[7, 8, 10, 11, 13]
3 (50)
[9, 10, 13]
0 3 (50)
[7, 8, 11]
2 (33.3)
[7, 11]
4 (66.7)
[810, 13]
2 (33.3)
[8, 10]
5 (83.3)
[811, 13]
1 (16.7)
[7]
0 2 (33.3)
[8, 9]
0 3 (50)
[7, 10, 13]
3 (50)
[10, 11, 13]
Discrete event simulation 7 (87.5) 1 (14.3)
[12]
1 (14.3)
[13]
6 (85.7)
[711, 13]
4 (57.1)
[9, 10, 12, 13]
0 3 (42.9)
[7, 8, 11]
2 (28.6)
[7, 11]
1 (14.3)
[13]
5 (71.4)
[810, 12, 13]
4 (57.1)
[8, 9, 11, 12]
0 4 (57.1)
[7, 10, 12, 13]
3 (42.9)
[8, 9, 12]
0 2 (28.6)
[11, 13]
4 (57.1)
[7, 10, 11, 13]
Agent-based models 2 (25) 0 0 2 (100)
[8, 13]
1 (50)
[13]
0 1 (50)
[8]
0 0 2 (100)
[8, 13]
1 (50)
[8]
0 1 (50)
[13]
1 (50)
[8]
0 1 (50)
[13]
1 (50)
[13]
System dynamics 5 (62.5) 0 5 (100)
[811, 13]
0 2 (40)
[9, 13]
3 (60)
[8, 10, 11]
2 (40)
[10, 11]
1 (20)
[11]
0 4 (80)
[810, 13]
5 (100)
[811, 13]
0 0 2 (40)
[8, 9]
0 3 (60)
[10, 11, 13]
3 (60)
[10, 11, 13]
Compartmental models 2 (25) 1 (50)
[6]
1 (50)
[8]
0 1 (50)
[6]
1 (50)
[8]
1 (50)
[8]
0 0 2 (100)
[6, 8]
2 (100)
[6, 8]
0 0 2 (100)
[6, 8]
0 0 0
  1. aDenominator out of 8 (total number of decision frameworks identified).
  2. bDenominator out of the number of frameworks that have discussed that specific modelling approach (i.e. second column).
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